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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
NACHT, LRR and PYD domains-containing protein 3
(Mouse)
TBA
Curated by
ChEMBL
Ligand
BDBM50465504
(CHEMBL4277889)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of NLRP3 in mouse BMDM assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by incubation f...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Mouse)
TBA
Curated by
ChEMBL
Ligand
BDBM50465504
(CHEMBL4277889)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
Inhibition of NLRP3 in mouse J774A.1 cells assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by inc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI