Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  300nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  300nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  300nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 30 mins followed by A...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed