Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
TBA

Curated by ChEMBL

LigandBDBM50530854(CHEMBL4456669)Copy SMILESCopy InChI

Affinity DataIC50:  880nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs befo...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
TBA

Curated by ChEMBL

LigandBDBM50530854(CHEMBL4456669)Copy SMILESCopy InChI

Affinity DataIC50:  880nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs befo...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI