Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

Target5-hydroxytryptamine receptor 2B(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]-spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50:  280nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50:  310nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50:  850nMAssay Description:Displacement of [3H]-SCH-23,390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50:  1.27E+3nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50:  2.55E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human 5-HT2B receptor transfected in CHO cell assessed as IP1 production incubated for 30 mins measured by HTRF detection methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed