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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427]
(Homo sapiens (Human))
Nurix Therapeutics
US Patent
Ligand
BDBM575676
(US11464802, Compound 39)
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Affinity Data
IC50: <1nM
Assay Description:
Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...
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Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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