Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 10 hits in this display
Beta-glucuronidase(Escherichia coli (strain K12))University of North Carolina At Chapel Hill
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Ki: 970nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Beta-galactosidase(Streptococcus agalactiae (Firmicutes))University of North Carolina At Chapel Hill
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Ki: 1.40E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Beta-glucuronidase(Escherichia coli (strain K12))University of North Carolina At Chapel Hill
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
EC50: 29nMAssay Description:PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair
BDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
EC50: 17.7nMAssay Description:PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair