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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
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Affinity Data
IC50: 40nM
Assay Description:
In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
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Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 460nM
Assay Description:
Inhibitory concentration against Sal2 (salivary gland carcinoma) cell line expressing active HER2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibitory concentration against Met cytoplasmic sequence; Reported as mean (variability <15%)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
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Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibitory concentration against p38 cytoplasmic sequence; Reported as mean (variability <15%)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibitory concentration against MAPKAP kinase 2 cytoplasmic sequence; Reported as mean (variability <15%)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibitory concentration against IGF-1R cytoplasmic sequence; Reported as mean (variability <15%)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM13923
(2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibitory concentration against FAK cytoplasmic sequence; Reported as mean (variability <15%)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI