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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Medical University of South Carolina
Ligand
BDBM26630
((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
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Affinity Data
IC50: 300nM
Assay Description:
The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Medical University of South Carolina
Ligand
BDBM26630
((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
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Copy InChI
Affinity Data
IC50: 600nM
pH: 7.0 T: 2°C
Assay Description:
The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM26630
((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
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Affinity Data
IC50: 1.11E+4nM
Assay Description:
Inhibition of IGF1R by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM26630
((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of IR by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI