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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  300nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  600nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of IGF1R by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of IR by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed