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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 0.820nM
Assay Description:
In vitro binding affinity towards alpha-1 adrenergic receptor in rat frontal cortex homogenate using of [3H]prazosin as radioligand
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 1.5nM
Assay Description:
In vitro binding affinity towards 5-hydroxytryptamine 2A receptor in rat tissue homogenate using [3H]ketanserin as radioligand
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Target Info
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CHEMBL
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Article
PubMed
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Target
D(1A) dopamine receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 16nM
Assay Description:
In vitro binding affinity towards Dopamine receptor D1 in rat tissue homogenate using [3H]-SCH- 23390 as radioligand
More data for this Ligand-Target Pair
Target Info
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Article
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Target
Histamine H1 receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 21nM
Assay Description:
In vitro binding affinity towards Histamine H1 receptor of rat frontal cortex homogenate by using radioligand [3H]pyrilamine
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
Histamine H1 receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 21.3nM
Assay Description:
Half-maximal inhibition of [3H]pyrilamine binding to Histamine H1 receptor in rat frontal cortex homogenate
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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CHEMBL
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In Depth
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Article
PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 50nM
Assay Description:
In vitro binding affinity towards Dopamine receptor D2 in rat tissue homogenate using [3H]-spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 110nM
Assay Description:
In vitro binding affinity towards Dopamine receptor D3 in Sf9 cell membranes using [3H]7-OH-DPAT as radioligand
More data for this Ligand-Target Pair
Target Info
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Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 209nM
Assay Description:
In vitro binding affinity towards alpha-2 adrenergic receptor in rat frontal cortex homogenate using of [3H]clonidine as radioligand
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
Muscarinic acetylcholine receptor M1
(Rat)
University of Siena
Curated by
ChEMBL
Ligand
BDBM50137978
((S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihy...)
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Affinity Data
Ki: 287nM
Assay Description:
In vitro binding affinity towards M1 receptor of rat frontal cortex homogenate by using radioligand [3H]QNB
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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