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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor
(Human)
National Institute of Diabetes
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Affinity Data
Ki: 9nM
Assay Description:
Binding affinity against beta-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of Dihydro-[3H]-alprenolol
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
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Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Affinity Data
Ki: 9nM
Assay Description:
Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
National Institute of Diabetes
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 700nM
Assay Description:
Binding affinity against beta-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of Dihydro-[3H]-alprenolol
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Affinity Data
Ki: 700nM
Assay Description:
Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Beta-2 adrenergic receptor
(Dog)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50087515
((R)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benz...)
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Affinity Data
Ki: 3.80E+4nM
Assay Description:
Binding of [3H]-dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Beta-2 adrenergic receptor
(Dog)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Copy InChI
Affinity Data
Ki: 5.00E+4nM
Assay Description:
Binding of [3H]-dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.30E+4nM
Assay Description:
Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Guinea pig)
National Institute of Diabetes
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Copy InChI
Affinity Data
Ki: 6.30E+4nM
Assay Description:
Binding affinity against beta-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of Dihydro-[3H]-alprenolol
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Human)
National Institute of Diabetes
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 800nM
Assay Description:
Agonistic potency at alpha-1 adrenergic receptor for the amine-induced increase of phosphatidylinositol breakdown in synaptoneurosomes from guinea pi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Affinity Data
EC50: >1.50E+3nM
Assay Description:
Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Guinea pig)
National Institute of Diabetes
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
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Affinity Data
EC50: >1.50E+3nM
Assay Description:
Agonistic potency at beta-1 adrenergic receptor for the percent maximal increase in contraction rate of isolated guinea pig atria
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor
(Human)
National Institute of Diabetes
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 100nM
Assay Description:
Agonistic potency at beta-1 adrenergic receptor for the percent maximal increase in contraction rate of isolated guinea pig atria
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50019057
((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.50E+3nM
Assay Description:
Agonistic potency at beta adrenergic receptor for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI