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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: 7nM
Assay Description:
Inhibition of MEK1 (unknown origin) assessed as phosphorylation of Erk2 preincubated for 30 mins followed by FAM-Erktide addition measured after 60 m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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Article
PubMed
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: 8nM
Assay Description:
Inhibition of C-Raf (unknown origin) assessed as phosphorylation of MEK1 after 45 mins by TR-FRET assay
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Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of ALK (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
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Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of IGF1R (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
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Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of DDR1 (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of MET (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Macrophage-stimulating protein receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of RON (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of AXL (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
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Article
PubMed
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of FLT3 (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of EGFR (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CDK-2 (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CDK-1 (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of InsR (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of FAK (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of ABL (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein-tyrosine kinase 6
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50443366
(CHEMBL3086065)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of BRK (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI