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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065285
(3-[1-(3-Bromo-5-tert-butyl-4-methoxy-phenyl)-meth-...)
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Affinity Data
IC50: 1.90E+4nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065285
(3-[1-(3-Bromo-5-tert-butyl-4-methoxy-phenyl)-meth-...)
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Affinity Data
IC50: 1.90E+4nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Mus musculus)
Sugen
Curated by
ChEMBL
Ligand
BDBM50065285
(3-[1-(3-Bromo-5-tert-butyl-4-methoxy-phenyl)-meth-...)
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Affinity Data
IC50: 4.66E+4nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065285
(3-[1-(3-Bromo-5-tert-butyl-4-methoxy-phenyl)-meth-...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065285
(3-[1-(3-Bromo-5-tert-butyl-4-methoxy-phenyl)-meth-...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI