Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27785(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27785(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Gsk

LigandPNGBDBM27785(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
Affinity DataIC50:  3.89E+3nMpH: 7.4 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Gsk

LigandPNGBDBM27785(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
Affinity DataIC50:  6.31E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitor binding to JNK3 was assessed by a fluorescence anisotropy competitive binding assay. The reaction mixture (JNK3 and fluorescently labelled ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed