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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Gsk
Ligand
BDBM27785
(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
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Affinity Data
IC50: 20nM
pH: 7.5 T: 2°C
Assay Description:
Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Gsk
Ligand
BDBM27785
(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
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Copy InChI
Affinity Data
IC50: 20nM
pH: 7.5 T: 2°C
Assay Description:
Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Gsk
Ligand
BDBM27785
(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
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Affinity Data
IC50: 3.89E+3nM
pH: 7.4 T: 2°C
Assay Description:
Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Gsk
Ligand
BDBM27785
(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
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Copy InChI
Affinity Data
IC50: 6.31E+3nM
pH: 7.5 T: 2°C
Assay Description:
Inhibitor binding to JNK3 was assessed by a fluorescence anisotropy competitive binding assay. The reaction mixture (JNK3 and fluorescently labelled ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI