Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 10 hits in this display
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
IC50: <100nMAssay Description:A compound's ability in selectively inhibiting EGFR exon 20 insertion mutations can be assessed using Ba/F3 cells, a murine pro-B cell line, whic...More data for this Ligand-Target Pair
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
IC50: 200nMAssay Description:Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
IC50: 600nMAssay Description:Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)
BDBM50029664(CHEMBL3353408 | US10227342, Example 56)