Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248464(CHEMBL491677 | N-[4-(isoindolin-2-yl)phenyl]-6',7'...)
Affinity DataIC50:  920nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248464(CHEMBL491677 | N-[4-(isoindolin-2-yl)phenyl]-6',7'...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248464(CHEMBL491677 | N-[4-(isoindolin-2-yl)phenyl]-6',7'...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248464(CHEMBL491677 | N-[4-(isoindolin-2-yl)phenyl]-6',7'...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of CDK4 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248464(CHEMBL491677 | N-[4-(isoindolin-2-yl)phenyl]-6',7'...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248464(CHEMBL491677 | N-[4-(isoindolin-2-yl)phenyl]-6',7'...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed