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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Abbott Laboratories
Ligand
BDBM27964
(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
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Affinity Data
IC50: 53nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Epidermal growth factor receptor [671-1210,L858R]
(Homo sapiens (Human))
Abbott Laboratories
Ligand
BDBM27964
(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
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Copy InChI
Affinity Data
IC50: 58nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM27964
(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
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Copy InChI
Affinity Data
IC50: 81nM
Assay Description:
Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM27964
(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 81nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM27964
(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 142nM
Assay Description:
Inhibition IGF1R phosphorylation in human MiaPaCa2 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI