Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  53nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  81nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  142nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed