Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505850(Dapansutrile | OLT-1177 | OLT1177)
Affinity DataIC50:  1nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505850(Dapansutrile | OLT-1177 | OLT1177)
Affinity DataIC50:  1nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta level incubated for 1 hr followed by ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505850(Dapansutrile | OLT-1177 | OLT1177)
Affinity DataIC50:  100nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells infected with FLA-ST assessed as inhibition of LPS- induced IL-1beta production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed