Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Vascular endothelial growth factor receptor 1
(Mus musculus)
Sugen
Curated by
ChEMBL
Ligand
BDBM50065273
(3-[1-(5-Methylsulfanyl-thiophen-2-yl)-meth-(Z)-yli...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.34E+3nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065273
(3-[1-(5-Methylsulfanyl-thiophen-2-yl)-meth-(Z)-yli...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065273
(3-[1-(5-Methylsulfanyl-thiophen-2-yl)-meth-(Z)-yli...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065273
(3-[1-(5-Methylsulfanyl-thiophen-2-yl)-meth-(Z)-yli...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Sugen
Curated by
ChEMBL
Ligand
BDBM50065273
(3-[1-(5-Methylsulfanyl-thiophen-2-yl)-meth-(Z)-yli...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI