Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 111 hits in this display   

Target5-hydroxytryptamine receptor 1B(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  0.260nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  0.260nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1B receptor using [3H]-5-HT trifluoroacetate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1D receptor using [3H]-5-HT trifluoroacetate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  0.790nMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  0.810nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.28nMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.28nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.36nMMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.44nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.45nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Bovine)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.5nMAssay Description:Compound was evaluated for inhibition of binding of [3H]-MK-91 to Alpha-2 adrenergic receptor in bovine pinealMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-clonidine from alpha2-adrenergic receptor in rat brain cortex after 30 mins by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.90nMAssay Description:The ability to displace [3H]clonidine from the Alpha-2 adrenergic receptor was determined in rat brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  2.51nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Pig)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  3.19nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Rabbit)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  4.90nMMore data for this Ligand-Target Pair
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Rabbit)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity towards Alpha-1A adrenergic receptor in rat submaxillary glandsMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  7.24nMMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Dog)
Unwersity of Misscuri

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  9.68nMMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(North American opossum)
University of Missouri

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards bovine clonal Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(North American opossum)
University of Missouri

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  15.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor(Mouse)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  15.5nMMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  15.8nMMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  16nMAssay Description:Affinity to Alpha-1 adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  16nMAssay Description:Affinity to human Alpha-2A adrenergic receptor determined by radioligand binding techniques from chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Guinea pig)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Pig)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for inhibition of binding of [3H]-MK-91 to Alpha-2 adrenergic receptor in porcine alpha2-cloneMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  24nMMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 1(Bovine)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor(Mouse)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  25.7nMMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(North American opossum)
University of Missouri

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  30.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(OK)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(OK)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Guinea pig)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  31.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Dog)
Unwersity of Misscuri

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  33nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Bovine)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  33.1nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Bovine)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Pig)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  35.5nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  37nMMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Bovine)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  38.0nMMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  59nMAssay Description:Affinity to human Alpha-2C adrenergic receptor determined by radioligand binding techniques from chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  71nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(North American opossum)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  114nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Human)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  148nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Hamster)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  158nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1B adrenergic receptor(Pig)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  158nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  185nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1B adrenergic receptor(Hamster)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  204nMAssay Description:Binding affinity towards hamster clonal Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  204nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2B adrenergic receptor(Human)
Neurogenetic

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  213nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  224nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Human)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  257nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  308nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  309nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1D adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  331nMAssay Description:Binding affinity towards rat clonal Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
National Children'S Medical Research Center

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  417nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  419nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  646nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Human)
Neurogenetic

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  754nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  794nMMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  794nMMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rat)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  824nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  832nMAssay Description:Affinity to human Alpha-1B adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.26E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.35E+3nMAssay Description:Affinity to human Alpha-1D adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-2B adrenergic receptor(Human)
Neurogenetic

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  1.78E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  2.14E+3nMMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Human)
Neurogenetic

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  2.98E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2B adrenergic receptor(Human)
Neurogenetic

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  5.37E+3nMAssay Description:Affinity to human Alpha-2B adrenergic receptor determined by radioligand binding techniques from chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataIC50:  5nMAssay Description:50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranesMore data for this Ligand-Target Pair
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataIC50:  300nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...More data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rat)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  339nMAssay Description:In vitro agonist potency towards Alpha-1B adrenergic receptor in rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  288nMAssay Description:In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferensMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  347nMAssay Description:In vitro agonist potency towards Alpha-1A adrenergic receptor in canine prostateMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  20nMAssay Description:Agonist potency at Alpha-1 adrenergic receptor assayed in rat-1 fibroblasts expressing human Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  3.30nMAssay Description:Agonist potency at Alpha-2A stably expressed in CHO cells.More data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: <2.51E+4nMAssay Description:Agonist potency at Alpha-1D adrenergic receptor assayed in rat-1 fibroblasts expressing human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: <2.51E+4nMAssay Description:Agonist potency at Alpha-1B adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: <5.01E+3nMAssay Description:Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: <5.01E+3nMAssay Description:Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  20nMAssay Description:Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  137nMAssay Description:Compound was tested for 5-hydroxytryptamine 1D like receptor-mediated vascular effect in rabbit saphenous vein (RSV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: <5.01E+3nMAssay Description:In vitro activation of human Alpha-1B receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  20nMAssay Description:In vitro activation of human alpha-1A receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...More data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: <5.01E+3nMAssay Description:In vitro activation of human alpha-1D receptor expressed in rat-1 fibroblasts via calcium using mobilization through the Gq coupled PLC pathway as fu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50: >4.00E+4nMAssay Description:External Assay ID: S1P3_EC50_CS_5HT1e_Agonist Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  426nMpH: 7.4 T: 23°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAlpha-1D adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  8.32E+3nMAssay Description:In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  70nMpH: 7.4 T: 23°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target5-hydroxytryptamine receptor 1E(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataEC50:  99nMpH: 7.4 T: 23°CAssay Description:The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Displayed 1 to 50 (of 111 total ) | Next | Last >>