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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
31
hits in this display
Target
Aurora kinase A
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: <4nM
Assay Description:
Inhibition of Aurora A (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Aurora kinase B
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: <13nM
Assay Description:
Inhibition of Aurora B (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: 14nM
Assay Description:
Inhibition of FLT3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
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DrugBank
antibodypedia
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >20nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: 260nM
Assay Description:
Inhibition of RSK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: 271nM
Assay Description:
Inhibition of LCK (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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Ligand Info
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Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: 360nM
Assay Description:
Inhibition of CHK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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B.MOAD
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Ephrin type-B receptor 4
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: 390nM
Assay Description:
Inhibition of EPHB4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of IGF1R (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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Ligand Info
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Article
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of MET (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of MST2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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GoogleScholar
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Article
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Target
Protein kinase C alpha type
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of PKCA (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of ROCK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Target
Testis-specific serine/threonine-protein kinase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of TSSK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
KEGG
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GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Copy InChI
Affinity Data
IC50: >500nM
Assay Description:
Inhibition of NEK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Copy InChI
Affinity Data
IC50: >500nM
Assay Description:
Inhibition of PLK3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of ERK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of CSNK1D (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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B.MOAD
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Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of CDK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of CAMK4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Copy InChI
Affinity Data
IC50: >500nM
Assay Description:
Inhibition of AKT1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
IC50: >500nM
Assay Description:
Inhibition of JAK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of GSK3b (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Affinity Data
IC50: >500nM
Assay Description:
Inhibition of IKKB (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
IC50: >500nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
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Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.100nM
Assay Description:
Binding affinity to Aurora B (unknown origin) after 45 mins by fluorescence-based thermal stability shift assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.0100nM
Assay Description:
Binding affinity to Aurora A (unknown origin) after 45 mins by fluorescence-based thermal stability shift assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50460773
(CHEMBL4227082)
Copy SMILES
Copy InChI
Affinity Data
EC50: 117nM
Assay Description:
Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI