Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 22 hits in this display
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 1.15nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 1.20nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 13nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 18nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 19nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 19nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 41nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 44nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 44nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 98nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 98nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 114nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 120nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 120nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 125nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 125nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 146nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 159nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 159nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569234(US11427563, Compound 101 | US11427563, Compound 16...)
IC50: 159nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair