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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50:  11nMAssay Description:PI 3-Kinase Gamma (E), PI 3-Kinase Delta (F):The TR-FRET Adapta™ Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50:  90nMAssay Description:PI 3-Kinase Alpha (A), Pb 3-Kinase Beta (B), Vps34 (C), PI 4-Kinase Beta (D):The luminescence-based ATP detection reagent KinaseGlo was obtained from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50:  100nMAssay Description:PI 3-Kinase Alpha (A), Pb 3-Kinase Beta (B), Vps34 (C), PI 4-Kinase Beta (D):The luminescence-based ATP detection reagent KinaseGlo was obtained from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50:  630nMAssay Description:PI 3-Kinase Gamma (E), PI 3-Kinase Delta (F):The TR-FRET Adapta™ Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50:  4.40E+3nMAssay Description:PI 3-Kinase Alpha (A), Pb 3-Kinase Beta (B), Vps34 (C), PI 4-Kinase Beta (D):The luminescence-based ATP detection reagent KinaseGlo was obtained from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Novartis

US Patent
LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50:  6.00E+3nMAssay Description:mTOR: Binding Assays are based on the binding and displacement of an Alexa Fluor® 647-labeled, ATP-competitive kinase inhibitors to the kinase of int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetPhosphatidylinositol 4-kinase beta(Human)
Novartis

US Patent
LigandPNGBDBM364535(Cis 3-[6-(1,3-Dimethyl-1H-pyrazol-4-yl)-pyrazin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:PI 3-Kinase Alpha (A), Pb 3-Kinase Beta (B), Vps34 (C), PI 4-Kinase Beta (D):The luminescence-based ATP detection reagent KinaseGlo was obtained from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent