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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Rat)
Universidade Federal Do Rio Grande Do Sul
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 90nM
Assay Description:
Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
D(4) dopamine receptor
(Human)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 170nM
Assay Description:
Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
D(4) dopamine receptor
(Human)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 180nM
Assay Description:
Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
Universidade Federal Do Rio Grande Do Sul
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Copy InChI
Affinity Data
Ki: 210nM
Assay Description:
Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rat)
Universidade Federal Do Rio Grande Do Sul
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Copy InChI
Affinity Data
Ki: 220nM
Assay Description:
Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rat)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 380nM
Assay Description:
Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rat)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Copy InChI
Affinity Data
Ki: 390nM
Assay Description:
Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rat)
Universidade Federal Do Rio Grande Do Sul
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 2.32E+3nM
Assay Description:
Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Alpha-2A adrenergic receptor [16-465]
(Rat)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 2.49E+3nM
Assay Description:
Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(Rat)
Universidade Federal Do Rio De Janeiro
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 2.50E+3nM
Assay Description:
Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Alpha-1B adrenergic receptor
(Rat)
Universidade Federal Do Rio De Janeiro
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Alpha-1B adrenergic receptor
(Rat)
Universidade Federal Do Rio De Janeiro
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 3.00E+3nM
Assay Description:
Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rat)
Universidade Federal Do Rio Grande Do Sul
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.82E+3nM
Assay Description:
Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rat)
Universidade Federal Do Rio Grande Do Sul
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.91E+3nM
Assay Description:
Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Human)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
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Affinity Data
Ki: 8.44E+3nM
Assay Description:
Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Human)
Universidade Federal De Goi£S
Curated by
ChEMBL
Ligand
BDBM50308002
(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.63E+3nM
Assay Description:
Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI