Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  310nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  400nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  650nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  790nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetD(4) dopamine receptor(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL

LigandBDBM50492798(CHEMBL2414355)Copy SMILESCopy InChI

Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI