Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 15 hits in this display
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 1.5nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 8nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 17nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 18nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 67nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 67nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 82nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 160nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 160nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 170nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 210nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 381nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
BDBM569237(US11427563, Compound 104 | US11427563, Compound 28)
IC50: 381nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair