Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365174BDBM365174(US9867833, Compound I-88(R) | 4-(3-(3-chlorobenzyl...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365174BDBM365174(US9867833, Compound I-88(R) | 4-(3-(3-chlorobenzyl...)
Affinity DataIC50: 6.36nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365174BDBM365174(US9867833, Compound I-88(R) | 4-(3-(3-chlorobenzyl...)
Affinity DataIC50: 6.36nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent