Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM50473567(CHEMBL165645)Copy SMILESCopy InChI

Affinity DataKi:  100nMAssay Description:In vitro binding affinity against alpha-2 adrenergic receptor of rat in presence of [3H]-RX 821002 radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM50473567(CHEMBL165645)Copy SMILESCopy InChI

Affinity DataKi:  158nMAssay Description:In vitro binding affinity was determined against serotonin reuptake site of rat in presence of [3H]paroxetine radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransporter(Rattus norvegicus)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM50473567(CHEMBL165645)Copy SMILESCopy InChI

Affinity DataKi:  794nMAssay Description:In vitro binding affinity was determined against NA (noradrenaline) reuptake site of rat in presence of [3H]nisoxetine radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI