Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
Medical University of Gdansk

Curated by ChEMBL

LigandBDBM50497434(CHEMBL3343697)Copy SMILESCopy InChI

Affinity DataKi:  416nMAssay Description:Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Medical University of Gdansk

Curated by ChEMBL

LigandBDBM50497434(CHEMBL3343697)Copy SMILESCopy InChI

Affinity DataKi:  3.81E+3nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNischarin(Rat)
Medical University of Gdansk

Curated by ChEMBL

LigandBDBM50497434(CHEMBL3343697)Copy SMILESCopy InChI

Affinity DataIC50:  1.48E+4nMAssay Description:Displacement of [3H]2BF1 from imidazoline I1 receptor in Sprague-Dawley rat kidney membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI