Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetEphrin type-B receptor 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human AXLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human ERBB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed