Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetStimulator of interferon genes protein [139-379, H232R](Homo sapiens (Human))
Janssen Biotech

US Patent
LigandPNGBDBM577474(US11472830, Cpd No. 6)
Affinity DataIC50:  23nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′, 3′cGAMP (cyclic (guanosine-(2′→5′)-monop...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573842((5R,7R,8R,12aR,14R,15R,15aS,18R)-7-(2-amino- 6-oxo...)
Affinity DataEC50:  2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM573842((5R,7R,8R,12aR,14R,15R,15aS,18R)-7-(2-amino- 6-oxo...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Janssen Biotech

US Patent
LigandPNGBDBM577474(US11472830, Cpd No. 6)
Affinity DataKd:  17nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Janssen Biotech

US Patent
LigandPNGBDBM577474(US11472830, Cpd No. 6)
Affinity DataKd:  310nMAssay Description:Thermofluor.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent