Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL

LigandBDBM50375341(CHEMBL261146)Copy SMILESCopy InChI

Affinity DataIC50:  77nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL

LigandBDBM50375341(CHEMBL261146)Copy SMILESCopy InChI

Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI