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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Insulin-like growth factor 1 receptor
(Human)
Osi Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50199630
(1-(3-(2-fluorobenzyloxy)phenyl)-3-cyclobutylimidaz...)
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Affinity Data
IC50: 224nM
Assay Description:
Inhibition of human recombinant GST-IGF1R activity
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Insulin-like growth factor 1 receptor
(Human)
Osi Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50199630
(1-(3-(2-fluorobenzyloxy)phenyl)-3-cyclobutylimidaz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.06E+3nM
Assay Description:
Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI