Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
LIM domain kinase 2
(Homo sapiens (Human))
Cardiff University
Curated by
ChEMBL
Ligand
BDBM50043501
(CHEMBL3355509)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.20nM
Assay Description:
Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
LIM domain kinase 2
(Homo sapiens (Human))
Cardiff University
Curated by
ChEMBL
Ligand
BDBM50043501
(CHEMBL3355509)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.90nM
Assay Description:
Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
LIM domain kinase 2
(Homo sapiens (Human))
Cardiff University
Curated by
ChEMBL
Ligand
BDBM50043501
(CHEMBL3355509)
Copy SMILES
Copy InChI
Affinity Data
IC50: 52nM
Assay Description:
Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
LIM domain kinase 1
(Homo sapiens (Human))
Cardiff University
Curated by
ChEMBL
Ligand
BDBM50043501
(CHEMBL3355509)
Copy SMILES
Copy InChI
Affinity Data
IC50: 145nM
Assay Description:
Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
LIM domain kinase 1
(Homo sapiens (Human))
Cardiff University
Curated by
ChEMBL
Ligand
BDBM50043501
(CHEMBL3355509)
Copy SMILES
Copy InChI
Affinity Data
IC50: 355nM
Assay Description:
Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI