Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hits in this display   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Jecure Therapeutics

Curated by ChEMBL

LigandBDBM50607495(CHEMBL5220818)Copy SMILESCopy InChI

Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS and nigericin-stimulated human PBMC cells assessed as reduction in IL-1beta release preincubated w...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI