Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 59 hits in this display
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 680nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 3.50E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 5.80E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 6.90E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 2.00E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 2.12E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 2.45E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 4.15E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 4.59E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 9.68E+4nMAssay Description:Inhibition of N-terminal His-tagged human ALKBH3 (1 to 286 residues) using m6A-ssDNA as substrate incubated for 30 mins by MALDI-TOF-MS analysisMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 2.50E+5nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assayMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: >2.50E+5nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assayMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 2.50E+5nMAssay Description:Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 5.00E+5nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
IC50: 6.40E+5nMAssay Description:Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assayMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Kd: 3.00E+3nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Kd: 3.40E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 313K temperatureMore data for this Ligand-Target Pair
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
BDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Kd: 3.10E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperatureMore data for this Ligand-Target Pair
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