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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
RNA-directed RNA polymerase
(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50181922
(2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
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Affinity Data
IC50: 760nM
Assay Description:
Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymerase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RNA-directed RNA polymerase
(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50181922
(2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90E+3nM
Assay Description:
Inhibitory activity against HCV 1a NS5B RNA dependent RNA polymerase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
DNA polymerase beta
(Human)
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50181922
(2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibitory activity against DNA polymerase beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
DNA polymerase alpha catalytic subunit
(Human)
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50181922
(2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibitory activity against DNA polymerase alpha
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RNA-directed RNA polymerase
(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50181922
(2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.80E+3nM
Assay Description:
Inhibition of HCV RNA replication in Huh5-2 cells after 48 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI