Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL

LigandBDBM50267892(CHEMBL4088092)Copy SMILESCopy InChI

Affinity DataIC50:  154nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

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In DepthDetails ArticlePubMed
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TargetSignal transducer and activator of transcription 5A(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL

LigandBDBM50267892(CHEMBL4088092)Copy SMILESCopy InChI

Affinity DataIC50:  4.97E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from C-terminal His6-tagged/N-terminal maltose-binding protein-tagged STAT5A SH2 domain (unknown...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI