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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Nodthera
Curated by
ChEMBL
Ligand
BDBM50601245
(CHEMBL5196139)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of NLRP3 inflammasome in LPS-pretreated PBMC (unknown origin) assessed as reduction in IL-1beta release pretreated for 30 mins followed by...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Nodthera
Curated by
ChEMBL
Ligand
BDBM50601245
(CHEMBL5196139)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
Inhibition of NLRP3 inflammasome in LPS-pretreated human THP1-ASC-GFP cells assessed as reduction in speck positive cells measured after 30 mins in p...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Nodthera
Curated by
ChEMBL
Ligand
BDBM50601245
(CHEMBL5196139)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of NLRP3 inflammasome in LPS-pretreated human whole blood assessed as reduction in IL-1beta release pretreated for 30 mins followed by ATP...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI