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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50245647((1S,2R,4aS,6aS,6bR,8aR,12aR,12bR,14bS)-1,2,6a,6b,9...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of cathepsin D (unknown origin) using hemoglobin as substrate after 30 min by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
China Pharmaceutical University

LigandPNGBDBM23203((1S,2R,4aS,6aS,6bR,12aR,12bR,14bS)-1,2,6a,6b,9,9,1...)
Affinity DataIC50:  5.70E+4nMpH: 7.2 T: 2°CAssay Description:The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
China Pharmaceutical University

LigandPNGBDBM50245647((1S,2R,4aS,6aS,6bR,8aR,12aR,12bR,14bS)-1,2,6a,6b,9...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins by microplate reader bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)

Curated by ChEMBL
LigandPNGBDBM50245647((1S,2R,4aS,6aS,6bR,8aR,12aR,12bR,14bS)-1,2,6a,6b,9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed