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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
OXA23 carbapenemase
(Acinetobacter baumannii)
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
Ki: 0.740nM
Assay Description:
Inhibition of Acinetobacter baumannii OXA-23 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every 10 ...
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Target
Carbapenem-hydrolyzing beta-lactamase KPC
()
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
Ki: 1.90nM
Assay Description:
Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...
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3D Structure (crystal)
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Target
VIM-1 metallo-beta-lactamase
(Klebsiella pneumoniae)
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
Ki: 8nM
Assay Description:
Inhibition of recombinant Escherichia coli VIM-1 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every...
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Target
Catalase
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of mammalian cathepsin A (unknown origin) using MCA-RPPGFSAFK-Dnp as substrate preincubated for 10 mins followed by substrate addition mea...
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Target
Prothrombin
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of mammalian thrombin (unknown origin) using Benz-FVR-AMC as substrate preincubated for 10 mins followed by substrate addition measured af...
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Target
Neutrophil elastase
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: 1.32E+5nM
Assay Description:
Inhibition of mammalian neutrophil elastase (unknown origin) using MeOSuc-AAVP-AMC as substrate preincubated for 10 mins followed by substrate additi...
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Target
Endothelin-converting enzyme 1
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: 4.31E+5nM
Assay Description:
Inhibition of mammalian ECE-1 (unknown origin) using MCA-RPPGFSAFK(DNP)-OH as substrate preincubated for 10 mins followed by substrate addition measu...
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Target
Cathepsin G
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: 6.66E+5nM
Assay Description:
Inhibition of mammalian cathepsin G (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured...
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Target Info
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Target
Chymotrypsinogen B2
(Homo sapiens)
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian chymotrypsin (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measure...
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Target
Angiotensin-converting enzyme 2
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian ACE-2 (unknown origin) using Mca-APK(Dnp) as substrate preincubated for 10 mins followed by substrate addition measured after...
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Target
Trypsin
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian trypsin (unknown origin) using N-Bz-R-AMC as substrate preincubated for 10 mins followed by substrate addition measured after...
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian MMP-9 (unknown origin) using McaPLGLDpaAR-NH2 as substrate preincubated for 10 mins followed by substrate addition measured a...
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Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian urokinase (unknown origin) using NGK-pNA as substrate preincubated for 10 mins followed by substrate addition measured after ...
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Target Info
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Target
Chymase
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian chymase (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured aft...
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Target
Dipeptidyl peptidase 2
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian DPP7 (unknown origin) using H-Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after...
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Target
Dipeptidyl peptidase 8
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian DPP8 (unknown origin) using Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 3...
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Target Info
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Target
Dipeptidyl peptidase 9
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian DPP9 (unknown origin) using Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 3...
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Target Info
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Target
Interstitial collagenase
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian MMP-1 (unknown origin) using McaPLGLDpaAR-NH2 as substrate preincubated for 10 mins followed by substrate addition measured a...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Plasminogen
(Homo sapiens (Human))
Qpex Biopharma
Curated by
ChEMBL
Ligand
BDBM50541448
(CHEMBL4633785)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of mammalian plasmin (unknown origin) using H-D-VLK-pNA as substrate preincubated for 10 mins followed by substrate addition measured afte...
More data for this Ligand-Target Pair
Target Info
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MMDB
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