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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
NADPH oxidase 5
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM50497268
(CHEMBL3347491)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
NADPH oxidase 1
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM50497268
(CHEMBL3347491)
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Affinity Data
IC50: 3.10E+4nM
Assay Description:
Inhibition of full length human NOX1 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...
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Target Info
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KEGG
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Article
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Target
Cytochrome b-245 heavy chain
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM50497268
(CHEMBL3347491)
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Affinity Data
IC50: 4.00E+4nM
Assay Description:
Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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In Depth
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Article
PubMed
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Target
Cytochrome b-245 heavy chain
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM50497268
(CHEMBL3347491)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.60E+4nM
Assay Description:
Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
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Article
PubMed
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Target
NADPH oxidase 4
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM50497268
(CHEMBL3347491)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of full length human NOX4 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI