Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetNADPH oxidase 5(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of full length human NOX1 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length human NOX4 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed