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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
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Affinity Data
IC50: 56nM
Assay Description:
Inhibition of TNKS2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 56nM
Assay Description:
Antagonistic activity against histamine H3 receptor in guinea pig ileum
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PubMed
PDB
3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Mus musculus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 56nM
Assay Description:
Inhibition of TNKS-2 in mouse L-Wnt-STF cells assessed as disruption of Wnt signaling after 24 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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MCE
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
TBA
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 131nM
Assay Description:
Antagonistic activity against histamine H3 receptor in guinea pig ileum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
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In Depth
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PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
TBA
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 131nM
Assay Description:
Inhibition of TNKS1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Mus musculus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 131nM
Assay Description:
Inhibition of TNKS-1 in mouse L-Wnt-STF cells assessed as disruption of Wnt signaling after 24 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 135nM
Assay Description:
Inhibition of recombinant human TNKS2 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biot...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: 135nM
Assay Description:
Inhibition of recombinant human TNKS2 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biot...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
TBA
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.88E+4nM
Assay Description:
Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
TBA
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.88E+4nM
Assay Description:
Inhibition of PARP1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MCE
PC cid
PC sid
PDB
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In Depth
Details
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
TBA
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.88E+4nM
Assay Description:
Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
TBA
Ligand
BDBM50007583
(CHEBI:62882 | CHEMBL562310)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.88E+4nM
Assay Description:
Inhibition of PAPR2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI