Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Istituto Di Scienze E Tecnologie Molecolari (Istm)

Curated by ChEMBL

LigandBDBM50240586(CHEMBL4098982)Copy SMILESCopy InChI

Affinity DataIC50:  1.10nMAssay Description:Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Istituto Di Scienze E Tecnologie Molecolari (Istm)

Curated by ChEMBL

LigandBDBM50240586(CHEMBL4098982)Copy SMILESCopy InChI

Affinity DataIC50:  91nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged XIAP BIR3 domain (241 to 356 residues) expressed in Escherichia coli BL21(DE3) cells afte...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI