Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

LigandBDBM50237252(CHEMBL4071923)Copy SMILESCopy InChI

Affinity DataEC50:  70nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

LigandBDBM50237252(CHEMBL4071923)Copy SMILESCopy InChI

Affinity DataEC50:  10nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI