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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-9 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of APMA-activated recombinant human GST-tagged MMP-14 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-7 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-1 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-3 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed