Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Novartis

US Patent

LigandBDBM297408(3-Amino-6-(4-fluoro-phenyl)-5-trifluoromethyl-pyri...)Copy SMILESCopy InChI

Affinity DataEC50:  60nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Novartis

US Patent

LigandBDBM297408(3-Amino-6-(4-fluoro-phenyl)-5-trifluoromethyl-pyri...)Copy SMILESCopy InChI

Affinity DataEC50:  60nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI