Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 19 hits in this display
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
IC50: 0.794nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
IC50: <3.16E+4nMAssay Description:Inhibition of PI3Kalpha in human BT474 cells assessed as reduction in Akt phosphorylation at Tyr308 residue after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)
IC50: <3.16E+4nMAssay Description:Inhibition of PI3Kbeta in human MDA-MB-468 cells assessed as reduction in Akt phosphorylation at Tyr308 residue after 2 hrsMore data for this Ligand-Target Pair
BDBM50274638(CHEMBL4126156 | US10858355, Example 4)