Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50116491(CHEMBL117072 | [22-Amino-4-carbamoyl-19-(3-guanidi...)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+4nMAssay Description:Ability to block the alpha4-beta7 integrin-MAdCAM-1 binding interaction using a protein ELISA formatMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50116491(CHEMBL117072 | [22-Amino-4-carbamoyl-19-(3-guanidi...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration affording 50% inhibition of alpha4-beta1 integrin binding to VCAM-1, using ELISA assay.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI