Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Sage Therapeutics

US Patent

LigandBDBM521590(US11149054, Compound 3266)Copy SMILESCopy InChI

Affinity DataEC50:  377nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Sage Therapeutics

US Patent

LigandBDBM521590(US11149054, Compound 3266)Copy SMILESCopy InChI

Affinity DataEC50:  148nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI