Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Cystic Fibrosis Foundation Therapeutics

US Patent

LigandBDBM301471(4-amino-5-[2-(difluoromethyl)pyrimidin-5-yl]-7-{1-...)Copy SMILESCopy InChI

Affinity DataEC50:  3.87nMAssay Description:Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI